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Gene: Dcaf8 (DDB1 and CUL4 associated factor 8) Mus musculus
Symbol: Dcaf8
Name: DDB1 and CUL4 associated factor 8
Description: Predicted to localize to several cellular components, including Cul4-RING E3 ubiquitin ligase complex; mitochondrion; and nucleoplasm. Human ortholog(s) of this gene implicated in giant axonal neuropathy 2. Is expressed in several structures, including brain; liver; lung; metanephros; and spleen. Orthologous to human DCAF8 (DDB1 and CUL4 associated factor 8); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408877; AA433120; AA792214; AU018973; C76055; D1Dau35e; D1Ucla4; DDB1- and CUL4-associated factor 8; expressed sequence AA433120; H326; MGC38511; WD repeat domain 42A; WD repeat-containing protein 42A; Wdr42a
Homo sapiens (human) : DCAF8 (DDB1 and CUL4 associated factor 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dcaf8 (DDB1 and CUL4 associated factor 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dcaf8 (DDB1 and CUL4 associated factor 8)
Pan paniscus (bonobo/pygmy chimpanzee) : DCAF8 (DDB1 and CUL4 associated factor 8)
Canis lupus familiaris (dog) : DCAF8 (DDB1 and CUL4 associated factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dcaf8 (DDB1 and CUL4 associated factor 8)
Sus scrofa (pig) : DCAF8 (DDB1 and CUL4 associated factor 8)
Chlorocebus sabaeus (African green monkey) : DCAF8 (DDB1 and CUL4 associated factor 8)
Heterocephalus glaber (naked mole-rat) : Dcaf8 (DDB1 and CUL4 associated factor 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1172,148,084 - 172,197,005 (+)EnsemblGRCm38mm10GRCm38
GRCm381172,148,015 - 172,196,393 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371174,078,146 - 174,126,524 (+)NCBIGRCm37mm9NCBIm37
MGSCv361173,984,817 - 174,032,141 (+)NCBImm8
Celera1175,002,206 - 175,052,357 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dcaf8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1619059
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.