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Gene: Arhgef25 (Rho guanine nucleotide exchange factor (GEF) 25) Mus musculus
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Symbol: Arhgef25
Name: Rho guanine nucleotide exchange factor (GEF) 25
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of Rho protein signal transduction. Localizes to the myofibril and plasma membrane. Is expressed in several structures, including acoustic ganglion; brain; gut gland; metanephros; and otocyst. Orthologous to human ARHGEF25 (Rho guanine nucleotide exchange factor 25); INTERACTS WITH 17alpha-ethynylestradiol; 4-hydroxyphenyl retinamide; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410008H17Rik; D10Ertd610e; GEFT; guanine nucleotide exchange factor GEFT; p63RhoGEF; rac/Cdc42/Rho exchange factor GEFT; rho guanine nucleotide exchange factor 25; rhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT
Orthologs:
Homo sapiens (human) : ARHGEF25 (Rho guanine nucleotide exchange factor 25)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Arhgef25 (Rho guanine nucleotide exchange factor 25)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef25 (Rho guanine nucleotide exchange factor 25)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGEF25 (Rho guanine nucleotide exchange factor 25)
Canis lupus familiaris (dog) : ARHGEF25 (Rho guanine nucleotide exchange factor 25)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef25 (Rho guanine nucleotide exchange factor 25)
Sus scrofa (pig) : ARHGEF25 (Rho guanine nucleotide exchange factor 25)
Chlorocebus sabaeus (African green monkey) : ARHGEF25 (Rho guanine nucleotide exchange factor 25)
Heterocephalus glaber (naked mole-rat) : Arhgef25 (Rho guanine nucleotide exchange factor 25)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl10127,182,525 - 127,190,083 (-)EnsemblGRCm38mm10GRCm38
GRCm3810127,182,521 - 127,190,083 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710126,619,577 - 126,627,110 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610126,585,478 - 126,592,968 (-)NCBImm8
Celera10129,575,551 - 129,583,084 (-)NCBICelera
Cytogenetic Map10 D3NCBI
cM Map1074.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Arhgef25
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1619220
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.