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Gene: Casq1 (calsequestrin 1) Mus musculus
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Symbol: Casq1
Name: calsequestrin 1
Description: Exhibits calcium ion binding activity. Involved in several processes, including regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; response to heat; and sarcomere organization. Localizes to the mitochondrial matrix and sarcoplasmic reticulum lumen. Predicted to colocalize with the Golgi apparatus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in several structures, including diaphragm; heart; lung; myotome; and skeletal muscle. Orthologous to human CASQ1 (calsequestrin 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: calmitine; calsequestrin, skeletal muscle isoform; calsequestrin-1; CSQ; CSQ-1; CSQ1; sCSQ
Orthologs:
Homo sapiens (human) : CASQ1 (calsequestrin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Casq1 (calsequestrin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casq1 (calsequestrin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CASQ1 (calsequestrin 1)
Canis lupus familiaris (dog) : CASQ1 (calsequestrin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casq1 (calsequestrin 1)
Sus scrofa (pig) : CASQ1 (calsequestrin 1)
Chlorocebus sabaeus (African green monkey) : CASQ1 (calsequestrin 1)
Heterocephalus glaber (naked mole-rat) : Casq1 (calsequestrin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1172,209,894 - 172,219,868 (-)EnsemblGRCm38mm10GRCm38
GRCm381172,209,894 - 172,219,895 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371174,140,025 - 174,150,026 (-)NCBIGRCm37mm9NCBIm37
MGSCv361174,047,013 - 174,056,514 (-)NCBImm8
Celera1175,065,863 - 175,075,868 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Casq1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1619288
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.