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Gene: Dact1 (dishevelled-binding antagonist of beta-catenin 1) Mus musculus
Symbol: Dact1
Name: dishevelled-binding antagonist of beta-catenin 1
Description: Exhibits delta-catenin binding activity; protein kinase A binding activity; and protein kinase C binding activity. Involved in several processes, including embryonic morphogenesis; positive regulation of fat cell differentiation; and regulation of signal transduction. Predicted to colocalize with beta-catenin destruction complex. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and genitourinary system. Orthologous to human DACT1 (dishevelled binding antagonist of beta catenin 1); INTERACTS WITH 1,2-dichloroethane; 1-chloro-2,4-dinitrobenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4921528D17Rik; AI115603; DAPPER; dapper 1; dapper antagonist of catenin 1; dapper homolog 1; dapper homolog 1, antagonist of beta-catenin; DAPPER1; Frd1; FRODO; frodo homolog; Frodo1; HDPR1; MDpr1; MTNG3; THYEX3; thymus expressed gene 3; thymus-expressed novel gene 3 protein
Homo sapiens (human) : DACT1 (dishevelled binding antagonist of beta catenin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dact1 (dishevelled-binding antagonist of beta-catenin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dact1 (dishevelled binding antagonist of beta catenin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DACT1 (dishevelled binding antagonist of beta catenin 1)
Canis lupus familiaris (dog) : DACT1 (dishevelled binding antagonist of beta catenin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dact1 (dishevelled binding antagonist of beta catenin 1)
Sus scrofa (pig) : DACT1 (dishevelled binding antagonist of beta catenin 1)
Chlorocebus sabaeus (African green monkey) : DACT1 (dishevelled binding antagonist of beta catenin 1)
Heterocephalus glaber (naked mole-rat) : Dact1 (dishevelled binding antagonist of beta catenin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1271,309,884 - 71,320,107 (+)EnsemblGRCm38mm10GRCm38
GRCm381271,309,884 - 71,320,107 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371272,410,871 - 72,421,094 (+)NCBIGRCm37mm9NCBIm37
MGSCv361272,228,589 - 72,237,499 (+)NCBImm8
Celera1272,410,534 - 72,420,756 (+)NCBICelera
Cytogenetic Map12C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dact1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1620056
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.