Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Nr2e3 (nuclear receptor subfamily 2, group E, member 3) Mus musculus
Analyze
Symbol: Nr2e3
Name: nuclear receptor subfamily 2, group E, member 3
Description: Exhibits DNA-binding transcription factor activity. Involved in several processes, including photoreceptor cell development; regulation of transcription by RNA polymerase II; and retina development in camera-type eye. Localizes to the nucleus and transcription factor complex. Used to study enhanced S-cone syndrome. Human ortholog(s) of this gene implicated in enhanced S-cone syndrome and retinitis pigmentosa 37. Is expressed in 1st branchial arch maxillary component; early conceptus; eye; and oocyte. Orthologous to human NR2E3 (nuclear receptor subfamily 2 group E member 3); PARTICIPATES IN retinitis pigmentosa pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A930035N01Rik; nuclear receptor subfamily 2 group E member 3; photoreceptor-specific nuclear receptor; PNR; rd7; retina-specific nuclear receptor; retinal degeneration 7; RNR
Orthologs:
Homo sapiens (human) : NR2E3 (nuclear receptor subfamily 2 group E member 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nr2e3 (nuclear receptor subfamily 2, group E, member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr2e3 (nuclear receptor subfamily 2 group E member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NR2E3 (nuclear receptor subfamily 2 group E member 3)
Canis lupus familiaris (dog) : NR2E3 (nuclear receptor subfamily 2 group E member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr2e3 (nuclear receptor subfamily 2 group E member 3)
Sus scrofa (pig) : NR2E3 (nuclear receptor subfamily 2 group E member 3)
Chlorocebus sabaeus (green monkey) : NR2E3 (nuclear receptor subfamily 2 group E member 3)
Heterocephalus glaber (naked mole-rat) : Nr2e3 (nuclear receptor subfamily 2 group E member 3)
more info ...
Related Pseudogenes: Gm18994  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl959,942,771 - 59,960,659 (-)Ensembl
GRCm38959,942,771 - 59,960,834 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37959,790,578 - 59,797,886 (-)NCBIGRCm37mm9NCBIm37
MGSCv36959,740,777 - 59,748,085 (-)NCBImm8
Celera957,170,930 - 57,178,240 (-)NCBICelera
Cytogenetic Map9 BNCBI
cM Map932.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nr2e3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1620083
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.