Zfp35 (zinc finger protein 35) - Chinchilla Research Resource Database
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Gene: Zfp35 (zinc finger protein 35) Mus musculus
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Symbol: Zfp35
Name: zinc finger protein 35
CRRD ID: 1620086
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in inflammatory response to antigenic stimulus and negative regulation of T-helper 2 cell differentiation. Predicted to localize to nucleus. Is expressed in bladder; early conceptus; inner cell mass; oocyte; and testis; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mszf13; mszf20-1; mszf28; mszf68; Zfp-3; Zfp-35; zinc finger protein 271; Znf271
Orthologs:
Related Pseudogenes: Gm18110  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391824,122,134 - 24,138,428 (+)NCBI
GRCm381823,989,634 - 24,005,371 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1823,989,632 - 24,005,376 (+)EnsemblGRCm38mm10GRCm38
MGSCv371824,148,135 - 24,163,872 (+)NCBIGRCm37mm9NCBIm37
MGSCv361824,132,644 - 24,148,381 (+)NCBImm8
Celera1824,479,709 - 24,495,427 (+)NCBICelera
Cytogenetic Map18A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

References

References - curated
1. RGD automated import pipeline
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1797234   PMID:2104800   PMID:2249852   PMID:9630514   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12904583  
PMID:14610273   PMID:15618518   PMID:16141072   PMID:16141073   PMID:18287559   PMID:18799693   PMID:19783676   PMID:20059953   PMID:20412781   PMID:21267068   PMID:21873635   PMID:32325033  


Genomics

Comparative Map Data
Zfp35
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391824,122,134 - 24,138,428 (+)NCBI
GRCm381823,989,634 - 24,005,371 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1823,989,632 - 24,005,376 (+)EnsemblGRCm38mm10GRCm38
MGSCv371824,148,135 - 24,163,872 (+)NCBIGRCm37mm9NCBIm37
MGSCv361824,132,644 - 24,148,381 (+)NCBImm8
Celera1824,479,709 - 24,495,427 (+)NCBICelera
Cytogenetic Map18A2NCBI
ZNF271P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1835,290,282 - 35,328,390 (+)EnsemblGRCh38hg38GRCh38
GRCh381835,290,272 - 35,310,766 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371832,870,236 - 32,890,730 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361831,124,298 - 31,142,072 (+)NCBINCBI36hg18NCBI36
Build 341831,124,297 - 31,142,072NCBI
Celera1829,678,140 - 29,698,629 (+)NCBI
Cytogenetic Map18q12.2NCBI
HuRef1829,729,853 - 29,750,349 (+)NCBIHuRef
CHM1_11832,797,211 - 32,817,713 (+)NCBICHM1_1
Zfp35
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01815,883,182 - 15,898,803 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1815,883,182 - 15,898,821 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01815,648,791 - 15,664,412 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41815,749,584 - 15,765,238 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11815,776,229 - 15,791,877 (+)NCBI
Celera1815,217,050 - 15,232,381 (+)NCBICelera
Cytogenetic Map18p12NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
CRRD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
14928307Manh83_mmandible shape 83 (mouse)18126902168Mouse
11354953Mom21_mmodifier of Min 21 (mouse)18128760766Mouse
12801458Intmrm3_mintima/media ratio modifier 3 (mouse)18131587699Mouse
12801462Intim3_mintima modifier 3 (mouse)18131587699Mouse
13207585Mwmlpt3_mMorris water maze latency to platform, training, 3 (mouse)18133414682Mouse
13207589Mwmlpa3_mMorris water maze latency to platform, all, 3 (mouse)18133414682Mouse
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060800000Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961139571Mouse
1558873Hrtfm7_mheart failure modifier 7 (mouse)Not determined18795390741954049Mouse
13504732Cath6_mcarotid atherosclerosis 6 (mouse)181350407347504073Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181389696666965891Mouse
1300994Pvcan3_mprotection against vaginal candidiasis 3 (mouse)Not determined181606658750066723Mouse
1301307Phospq1_mphospholipid QTL 1 (mouse)Not determined181800665152006806Mouse
12910787Pwbwq18_mpost-weaning body weight QTL 18 (mouse)181813247230437766Mouse
12910805Pwbwq17_mpost-weaning body weight QTL 17 (mouse)181813247230437766Mouse
12910819Ogrq6_moverall growth rate QTL 6 (mouse)181813247230437766Mouse
1558743Kcal1_mkilocalorie 1 (mouse)Not determined181888582152885939Mouse
1300638Im7_mimmunoregulatory 7 (mouse)Not determined181888582152885939Mouse
11532709Sluc41_msusceptibility to lung cancer 41 (mouse)182082063757457636Mouse
13463476Hctq8_mhematocrit QTL 8 (mouse)182108452755084674Mouse
1301950Otx2m1_morthodenticle homolog 2 (Drosophila) modifier 1 (mouse)Not determined182143562536054687Mouse
1301570Sluc14_msusceptibility to lung cancer 14 (mouse)Not determined182248686156487074Mouse
1300877Adip8_madiposity 8 (mouse)Not determined182248686156487074Mouse
11532710Sluc41a_msusceptibility to lung cancer 41a (mouse)182248686156487074Mouse
11532715Sluc41b_msusceptibility to lung cancer 41b (mouse)182248686156487074Mouse
11532716Sluc41c_msusceptibility to lung cancer 41c (mouse)182248686156487074Mouse
4142031Moen1_mmodifier of engrailed QTL 1 (mouse)Not determined182398250757982677Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:300
Count of miRNA genes:260
Interacting mature miRNAs:275
Transcripts:ENSMUST00000074941
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000074941   ⟹   ENSMUSP00000074475
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1823,989,632 - 24,005,376 (+)Ensembl
RefSeq Acc Id: NM_011755   ⟹   NP_035885
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391824,122,691 - 24,138,428 (+)NCBI
GRCm381823,989,634 - 24,005,371 (+)ENTREZGENE
MGSCv371824,148,135 - 24,163,872 (+)RGD
Celera1824,479,709 - 24,495,427 (+)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036161135   ⟹   XP_036017028
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391824,122,134 - 24,137,787 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_035885   ⟸   NM_011755
- UniProtKB: P15620 (UniProtKB/Swiss-Prot),   Q3V142 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000074475   ⟸   ENSMUST00000074941
RefSeq Acc Id: XP_036017028   ⟸   XM_036161135
- Peptide Label: isoform X1
Protein Domains
C2H2-type

Promoters
RGD ID:13677254
Promoter ID:EPDNEW_M22776
Type:multiple initiation site
Name:Zfp35_1
Description:Mus musculus zinc finger protein 35 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381823,989,681 - 23,989,741EPDNEW
RGD ID:6829624
Promoter ID:MM_KWN:24765
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000084942
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361824,147,836 - 24,148,336 (+)MPROMDB
RGD ID:6849426
Promoter ID:EP33039
Type:single initiation site
Name:MM_ZF35
Description:Zinc finger 35
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Tissues & Cell Lines:testes, spermatocytes, pachytene stage
Experiment Methods:Sequencing of a full-length cDNA; Primer extension
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv371824,148,180 - 24,148,240EPD
MGSCv361824,148,180 - 24,148,240EPD

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99179 AgrOrtholog
Ensembl Genes ENSMUSG00000063281 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000074475 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000074941 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22694 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:99179 ENTREZGENE
NCBI Gene 22694 ENTREZGENE
Pfam zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Zfp35 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.290596 ENTREZGENE
UniProt O88236_MOUSE UniProtKB/TrEMBL
  P15620 ENTREZGENE
  Q3TXW6_MOUSE UniProtKB/TrEMBL
  Q3V142 ENTREZGENE, UniProtKB/TrEMBL
  Q9QWN0_MOUSE UniProtKB/TrEMBL
  Q9QWN1_MOUSE UniProtKB/TrEMBL
  Q9QWN2_MOUSE UniProtKB/TrEMBL
  ZN271_MOUSE UniProtKB/Swiss-Prot