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Gene: Ttll5 (tubulin tyrosine ligase-like family, member 5) Mus musculus
Symbol: Ttll5
Name: tubulin tyrosine ligase-like family, member 5
Description: Predicted to have ATP binding activity and ligase activity. Involved in fertilization; protein polyglutamylation; and sperm axoneme assembly. Localizes to 9+0 non-motile cilium and ciliary basal body. Human ortholog(s) of this gene implicated in cone-rod dystrophy 19. Is expressed in choroid invagination; diencephalon roof plate; medulla oblongata part of 4th ventricle choroid plexus; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human TTLL5 (tubulin tyrosine ligase like 5); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700048H13Rik; 2310009M18Rik; 4930556H18Rik; AI428864; D630041K24Rik; mKIAA0998; polyglutamylase; R75373; STAMP; tubulin polyglutamylase TTLL5; tubulin tyrosine ligase like family 5; tubulin--tyrosine ligase-like protein 5
Homo sapiens (human) : TTLL5 (tubulin tyrosine ligase like 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ttll5 (tubulin tyrosine ligase like 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttll5 (tubulin tyrosine ligase like 5)
Pan paniscus (bonobo/pygmy chimpanzee) : TTLL5 (tubulin tyrosine ligase like 5)
Canis lupus familiaris (dog) : TTLL5 (tubulin tyrosine ligase like 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttll5 (tubulin tyrosine ligase like 5)
Sus scrofa (pig) : TTLL5 (tubulin tyrosine ligase like 5)
Chlorocebus sabaeus (African green monkey) : TTLL5 (tubulin tyrosine ligase like 5)
Heterocephalus glaber (naked mole-rat) : Ttll5 (tubulin tyrosine ligase like 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1285,824,659 - 86,061,893 (+)EnsemblGRCm38mm10GRCm38
GRCm381285,824,693 - 86,053,760 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371287,165,900 - 87,394,710 (+)NCBIGRCm37mm9NCBIm37
MGSCv361286,713,813 - 86,943,005 (+)NCBImm8
Celera1287,285,084 - 87,513,908 (+)NCBICelera
Cytogenetic Map12D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ttll5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1620469
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.