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Gene: Hax1 (HCLS1 associated X-1) Mus musculus
Symbol: Hax1
Name: HCLS1 associated X-1
Description: Predicted to have interleukin-1 binding activity; protein N-terminus binding activity; and protein domain specific binding activity. Predicted to be involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of actin cytoskeleton organization. Localizes to several cellular components, including the actin cytoskeleton; lamellipodium; and sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in severe congenital neutropenia. Is expressed in coelomic epithelium of testis; ovary; and testis mesenchyme. Orthologous to human HAX1 (HCLS1 associated protein X-1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HAX-1; HCLS1-associated protein X-1; HS1 binding protein; HS1-associated protein X-1; HS1-associating protein X-1; HS1-binding protein 1; Hs1bp1; HSP1BP-1; mHAX-1s; SIG-111; Silg111
Homo sapiens (human) : HAX1 (HCLS1 associated protein X-1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hax1 (HCLS1 associated protein X-1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hax1 (HCLS1 associated protein X-1)
Pan paniscus (bonobo/pygmy chimpanzee) : HAX1 (HCLS1 associated protein X-1)
Canis lupus familiaris (dog) : HAX1 (HCLS1 associated protein X-1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hax1 (HCLS1 associated protein X-1)
Sus scrofa (pig) : HAX1 (HCLS1 associated protein X-1)
Chlorocebus sabaeus (African green monkey) : HAX1 (HCLS1 associated protein X-1)
Heterocephalus glaber (naked mole-rat) : Hax1 (HCLS1 associated protein X-1)
more info ...
Related Pseudogenes: Gm14270   Gm18013   Gm18075  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl389,995,446 - 89,998,780 (-)Ensembl
GRCm38389,995,446 - 89,998,716 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37389,799,379 - 89,802,608 (-)NCBIGRCm37mm9NCBIm37
MGSCv36390,081,384 - 90,084,613 (-)NCBImm8
Celera390,031,986 - 90,035,256 (-)NCBICelera
Cytogenetic Map3 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hax1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1620872
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.