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Gene: Dennd1a (DENN/MADD domain containing 1A) Mus musculus
Symbol: Dennd1a
Name: DENN/MADD domain containing 1A
Description: Exhibits Rab guanyl-nucleotide exchange factor activity; SH3 domain binding activity; and phosphatidylinositol-3-phosphate binding activity. Involved in endocytic recycling; positive regulation of GTPase activity; and synaptic vesicle endocytosis. Localizes to several cellular components, including the clathrin-coated vesicle membrane; dendrite; and neuronal cell body. Orthologous to human DENND1A (DENN domain containing 1A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6030446I19Rik; connecdenn; connecdenn 1; DENN domain-containing protein 1A; MGC38995
Homo sapiens (human) : DENND1A (DENN domain containing 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dennd1a (DENN domain containing 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dennd1a (DENN domain containing 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : DENND1A (DENN domain containing 1A)
Canis lupus familiaris (dog) : DENND1A (DENN domain containing 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dennd1a (DENN domain containing 1A)
Sus scrofa (pig) : DENND1A (DENN domain containing 1A)
Chlorocebus sabaeus (African green monkey) : DENND1A (DENN domain containing 1A)
Heterocephalus glaber (naked mole-rat) : Dennd1a (DENN domain containing 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl237,798,991 - 38,287,390 (-)Ensembl
GRCm38237,798,990 - 38,287,410 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37237,654,510 - 38,142,904 (-)NCBIGRCm37mm9NCBIm37
MGSCv36237,621,000 - 38,109,356 (-)NCBImm8
Celera237,484,305 - 37,845,059 (-)NCBICelera
Cytogenetic Map2BNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dennd1a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1621336
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.