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Gene: Rassf1 (Ras association (RalGDS/AF-6) domain family member 1) Mus musculus
Symbol: Rassf1
Name: Ras association (RalGDS/AF-6) domain family member 1
Description: Predicted to have identical protein binding activity; protein N-terminus binding activity; and protein heterodimerization activity. Predicted to be involved in several processes, including negative regulation of cell cycle; positive regulation of protein ubiquitination; and protein stabilization. Predicted to localize to the microtubule cytoskeleton and nucleus. Human ortholog(s) of this gene implicated in breast cancer; reproductive organ cancer (multiple); transitional cell carcinoma; and urinary system cancer (multiple). Is expressed in liver and metanephros. Orthologous to human RASSF1 (Ras association domain family member 1); PARTICIPATES IN p53 signaling pathway; non-small cell lung carcinoma pathway; urinary bladder cancer pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 123F protein; 123F2; AA536941; AU044980; NORE2A; Ras association (RalGDS/AF-6) domain family 1; ras association domain-containing protein 1; Rassf1A; RASSF1A tumor suppressor; Rassf1B; Rassf1C; RDA32; REH3P21
Homo sapiens (human) : RASSF1 (Ras association domain family member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rassf1 (Ras association domain family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rassf1 (Ras association domain family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RASSF1 (Ras association domain family member 1)
Canis lupus familiaris (dog) : RASSF1 (Ras association domain family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rassf1 (Ras association domain family member 1)
Sus scrofa (pig) : RASSF1 (Ras association domain family member 1)
Chlorocebus sabaeus (African green monkey) : RASSF1 (Ras association domain family member 1)
Heterocephalus glaber (naked mole-rat) : Rassf1 (Ras association domain family member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl9107,551,555 - 107,562,267 (+)Ensembl
GRCm389107,551,434 - 107,562,267 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379107,456,987 - 107,464,591 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,412,757 - 107,420,361 (+)NCBImm8
Celera9107,160,318 - 107,171,016 (+)NCBICelera
Cytogenetic Map9 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rassf1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1621553
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.