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Gene: Mef2c (myocyte enhancer factor 2C) Mus musculus
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Symbol: Mef2c
Name: myocyte enhancer factor 2C
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; generation of neurons; and modulation of chemical synaptic transmission. Localizes to the nucleus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 20. Is expressed in several structures, including alimentary system; central nervous system; heart; limb; and urinary system. Orthologous to human MEF2C (myocyte enhancer factor 2C); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5430401D19Rik; 9930028G15Rik; AV011172; Mef2; myocyte-specific enhancer factor 2C
Orthologs:
Homo sapiens (human) : MEF2C (myocyte enhancer factor 2C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mef2c (myocyte enhancer factor 2C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mef2c (myocyte enhancer factor 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : MEF2C (myocyte enhancer factor 2C)
Canis lupus familiaris (dog) : MEF2C (myocyte enhancer factor 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mef2c (myocyte enhancer factor 2C)
Sus scrofa (pig) : MEF2C (myocyte enhancer factor 2C)
Chlorocebus sabaeus (green monkey) : MEF2C (myocyte enhancer factor 2C)
Heterocephalus glaber (naked mole-rat) : Mef2c (myocyte enhancer factor 2C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1383,504,034 - 83,667,080 (+)Ensembl
GRCm381383,504,017 - 83,667,079 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371383,643,033 - 83,806,684 (+)NCBIGRCm37mm9NCBIm37
MGSCv361383,981,532 - 84,141,286 (+)NCBImm8
Celera1385,760,645 - 85,921,930 (+)NCBICelera
Cytogenetic Map13 C3NCBI
cM Map1343.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mef2c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1621607
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.