Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Mef2c (myocyte enhancer factor 2C) Mus musculus
Symbol: Mef2c
Name: myocyte enhancer factor 2C
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; generation of neurons; and modulation of chemical synaptic transmission. Localizes to the nucleus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 20. Is expressed in several structures, including alimentary system; central nervous system; heart; limb; and urinary system. Orthologous to human MEF2C (myocyte enhancer factor 2C); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5430401D19Rik; 9930028G15Rik; AV011172; Mef2; myocyte-specific enhancer factor 2C
Homo sapiens (human) : MEF2C (myocyte enhancer factor 2C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mef2c (myocyte enhancer factor 2C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mef2c (myocyte enhancer factor 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : MEF2C (myocyte enhancer factor 2C)
Canis lupus familiaris (dog) : MEF2C (myocyte enhancer factor 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mef2c (myocyte enhancer factor 2C)
Sus scrofa (pig) : MEF2C (myocyte enhancer factor 2C)
Chlorocebus sabaeus (green monkey) : MEF2C (myocyte enhancer factor 2C)
Heterocephalus glaber (naked mole-rat) : Mef2c (myocyte enhancer factor 2C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1383,504,034 - 83,667,080 (+)Ensembl
GRCm381383,504,017 - 83,667,079 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371383,643,033 - 83,806,684 (+)NCBIGRCm37mm9NCBIm37
MGSCv361383,981,532 - 84,141,286 (+)NCBImm8
Celera1385,760,645 - 85,921,930 (+)NCBICelera
Cytogenetic Map13 C3NCBI
cM Map1343.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mef2c
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1621607
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.