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Gene: Kmt2e (lysine (K)-specific methyltransferase 2E) Mus musculus
Symbol: Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Description: Predicted to have enzyme binding activity and methylated histone binding activity. Involved in several processes, including DNA methylation; erythrocyte differentiation; and neutrophil activation. Predicted to localize to the nuclear body; protein-containing complex; and transcriptionally active chromatin. Human ortholog(s) of this gene implicated in autistic disorder and cervical cancer. Is expressed in several structures, including alimentary system; eye; heart; metanephros; and nervous system. Orthologous to human KMT2E (lysine methyltransferase 2E); PARTICIPATES IN histone modification pathway; lysine degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810033J14Rik; 9530077A04Rik; D230038D11Rik; FLJ10078; histone-lysine N-methyltransferase 2E; histone-lysine N-methyltransferase MLL5; inactive histone-lysine N-methyltransferase 2E; inactive lysine N-methyltransferase 2E; lysine N-methyltransferase 2E; Mll5; myeloid/lymphoid or mixed-lineage leukemia 5; myeloid/lymphoid or mixed-lineage leukemia protein 5 homolog; NKp44L
Homo sapiens (human) : KMT2E (lysine methyltransferase 2E)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kmt2e (lysine methyltransferase 2E)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kmt2e (lysine methyltransferase 2E)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT2E (lysine methyltransferase 2E)
Canis lupus familiaris (dog) : KMT2E (lysine methyltransferase 2E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt2e (lysine methyltransferase 2E)
Sus scrofa (pig) : KMT2E (lysine methyltransferase 2E)
Chlorocebus sabaeus (African green monkey) : KMT2E (lysine methyltransferase 2E)
Heterocephalus glaber (naked mole-rat) : Kmt2e (lysine methyltransferase 2E)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl523,434,441 - 23,504,235 (+)Ensembl
GRCm38523,433,036 - 23,504,235 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37522,940,247 - 23,010,047 (+)NCBIGRCm37mm9NCBIm37
MGSCv36522,474,922 - 22,544,722 (+)NCBImm8
Celera520,371,485 - 20,442,294 (+)NCBICelera
Cytogenetic Map5 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Kmt2e
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1622294
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.