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Gene: Mark3 (MAP/microtubule affinity regulating kinase 3) Mus musculus
Symbol: Mark3
Name: MAP/microtubule affinity regulating kinase 3
Description: Predicted to have protein serine/threonine kinase activity and tau-protein kinase activity. Predicted to be involved in several processes, including negative regulation of hippo signaling; peptidyl-serine autophosphorylation; and positive regulation of protein binding activity. Predicted to localize to the cytoplasm; dendrite; and plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Orthologous to human MARK3 (microtubule affinity regulating kinase 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1600015G02Rik; A430080F22Rik; C-TAK1; ELKL motif kinase 2; EMK-2; Emk2; EMK2/MARK3 serine-threonine protein kinase; ETK-1; ETK1; KIAA4230; MAP/microtubule affinity-regulating kinase 3; MPK-10; MPK10
Homo sapiens (human) : MARK3 (microtubule affinity regulating kinase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mark3 (microtubule affinity regulating kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mark3 (microtubule affinity regulating kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : MARK3 (microtubule affinity regulating kinase 3)
Canis lupus familiaris (dog) : MARK3 (microtubule affinity regulating kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mark3 (microtubule affinity regulating kinase 3)
Sus scrofa (pig) : MARK3 (microtubule affinity regulating kinase 3)
Chlorocebus sabaeus (green monkey) : MARK3 (microtubule affinity regulating kinase 3)
Heterocephalus glaber (naked mole-rat) : Mark3 (microtubule affinity regulating kinase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12111,574,523 - 111,656,221 (+)Ensembl
GRCm3812111,574,505 - 111,656,227 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712112,812,721 - 112,894,438 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612112,022,777 - 112,104,031 (+)NCBImm8
Celera12112,768,826 - 112,852,637 (+)NCBICelera
Cytogenetic Map12 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mark3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1622386
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.