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Gene: Btnl2 (butyrophilin-like 2) Mus musculus
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Symbol: Btnl2
Name: butyrophilin-like 2
CRRD ID: 1622608
Description: Exhibits signaling receptor binding activity. Involved in negative regulation of T cell receptor signaling pathway; positive regulation of T cell proliferation; and positive regulation of interleukin-2 production. Predicted to localize to external side of plasma membrane. Is expressed in intestine and skeletal muscle. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); berylliosis; coronary artery disease; and sarcoidosis. Orthologous to human BTNL2 (butyrophilin like 2); INTERACTS WITH 4-hydroxyphenyl retinamide; buta-1,3-diene; folic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BTL; BTL-II; Btl2; BTLN2; butyrophilin-like protein 2; butyrophylin-like MHC class II associated; Gm315; NG; NG9
Orthologs:
Homo sapiens (human) : BTNL2 (butyrophilin like 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Btnl2 (butyrophilin-like 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Btnl2 (butyrophilin like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : BTNL2 (butyrophilin like 2)
Canis lupus familiaris (dog) : BTNL2 (butyrophilin like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Btnl2 (butyrophilin like 2)
Sus scrofa (pig) : BTNL2 (butyrophilin like 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,573,763 - 34,588,466 (+)NCBI
GRCm381734,354,789 - 34,369,492 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,354,822 - 34,369,495 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,491,767 - 34,506,437 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,962,403 - 33,977,115 (+)NCBImm8
Celera1737,117,517 - 37,137,992 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Btnl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1622608
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.