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Gene: Aim2 (absent in melanoma 2) Mus musculus
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Symbol: Aim2
Name: absent in melanoma 2
Description: Exhibits double-stranded DNA binding activity and identical protein binding activity. Involved in several processes, including cellular response to interferon-beta; positive regulation of interleukin-1 beta secretion; and regulation of defense response. Localizes to the AIM2 inflammasome complex. Orthologous to human AIM2 (absent in melanoma 2); PARTICIPATES IN interleukin-1 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; buta-1,3-diene; diclofenac.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gm1313; ifi-210; Ifi210; interferon-inducible protein 210; interferon-inducible protein AIM2; interferon-inducible protein p210
Orthologs:
Homo sapiens (human) : AIM2 (absent in melanoma 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aim2 (absent in melanoma 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : AIM2 (absent in melanoma 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aim2 (absent in melanoma 2)
Chlorocebus sabaeus (African green monkey) : AIM2 (absent in melanoma 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1173,350,879 - 173,466,040 (+)EnsemblGRCm38mm10GRCm38
GRCm381173,349,547 - 173,466,040 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371175,350,735 - 175,396,171 (+)NCBIGRCm37mm9NCBIm37
MGSCv361175,298,822 - 175,302,715 (+)NCBImm8
Celera1176,275,753 - 176,321,623 (+)NCBICelera
Cytogenetic Map1H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Aim2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1622795
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.