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Gene: Rexo4 (REX4, 3'-5' exonuclease) Mus musculus
Symbol: Rexo4
Name: REX4, 3'-5' exonuclease
Description: Predicted to have nuclease activity; single-stranded DNA binding activity; and transcription coactivator activity. Predicted to be involved in DNA metabolic process and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear speck and nucleolus. Is expressed in limb and limb mesenchyme. Orthologous to human REXO4 (REX4 homolog, 3'-5' exonuclease); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: exonuclease XPMC2; Gm111; prevents mitotic catastrophe 2 protein homolog; Rex4; REX4, RNA exonuclease 4 homolog; RNA exonuclease 4; Xenopus prevents mitotic catastrophe 2 homolog; XPMC2 prevents mitotic catastrophe 2 homolog; Xpmc2h
Homo sapiens (human) : REXO4 (REX4 homolog, 3'-5' exonuclease)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rexo4 (REX4 homolog, 3'-5' exonuclease)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rexo4 (REX4 homolog, 3'-5' exonuclease)
Pan paniscus (bonobo/pygmy chimpanzee) : REXO4 (REX4 homolog, 3'-5' exonuclease)
Canis lupus familiaris (dog) : REXO4 (REX4 homolog, 3'-5' exonuclease)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rexo4 (REX4 homolog, 3'-5' exonuclease)
Sus scrofa (pig) : REXO4 (REX4 homolog, 3'-5' exonuclease)
more info ...
Related Pseudogenes: Gm14140   Gm8352  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38226,953,559 - 26,964,386 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37226,809,083 - 26,819,906 (-)NCBIGRCm37mm9NCBIm37
MGSCv36226,775,572 - 26,786,395 (-)NCBImm8
Celera226,663,308 - 26,673,885 (-)NCBICelera
Cytogenetic Map2 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Rexo4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1622969
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.