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Gene: Pdhx (pyruvate dehydrogenase complex, component X) Mus musculus
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Symbol: Pdhx
Name: pyruvate dehydrogenase complex, component X
Description: Predicted to contribute to pyruvate dehydrogenase (NAD+) activity. Predicted to be involved in mitochondrial acetyl-CoA biosynthetic process from pyruvate. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Is expressed in several structures, including alimentary system; musculature; nervous system; sensory organ; and urinary system. Orthologous to human PDHX (pyruvate dehydrogenase complex component X); PARTICIPATES IN pyruvate metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI481367; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (E3-binding protein) (proX); E3bp; lipoyl-containing pyruvate dehydrogenase complex component X; Pdx1; pyruvate dehydrogenase protein X component, mitochondrial
Orthologs:
Homo sapiens (human) : PDHX (pyruvate dehydrogenase complex component X)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdhx (pyruvate dehydrogenase complex, component X)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdhx (pyruvate dehydrogenase complex component X)
Pan paniscus (bonobo/pygmy chimpanzee) : PDHX (pyruvate dehydrogenase complex component X)
Canis lupus familiaris (dog) : PDHX (pyruvate dehydrogenase complex component X)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdhx (pyruvate dehydrogenase complex component X)
Sus scrofa (pig) : PDHX (pyruvate dehydrogenase complex component X)
more info ...
Related Pseudogenes: Gm18908  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl2103,021,075 - 103,073,513 (-)Ensembl
GRCm382103,021,055 - 103,073,513 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372102,861,212 - 102,913,670 (-)NCBIGRCm37mm9NCBIm37
MGSCv362102,821,916 - 102,874,350 (-)NCBImm8
Celera2104,263,925 - 104,317,607 (-)NCBICelera
Cytogenetic Map2 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pdhx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1623264
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.