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Gene: Pdhx (pyruvate dehydrogenase complex, component X) Mus musculus
Symbol: Pdhx
Name: pyruvate dehydrogenase complex, component X
Description: Predicted to contribute to pyruvate dehydrogenase (NAD+) activity. Predicted to be involved in mitochondrial acetyl-CoA biosynthetic process from pyruvate. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Is expressed in several structures, including alimentary system; musculature; nervous system; sensory organ; and urinary system. Orthologous to human PDHX (pyruvate dehydrogenase complex component X); PARTICIPATES IN pyruvate metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI481367; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (E3-binding protein) (proX); E3bp; lipoyl-containing pyruvate dehydrogenase complex component X; Pdx1; pyruvate dehydrogenase protein X component, mitochondrial
Homo sapiens (human) : PDHX (pyruvate dehydrogenase complex component X)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdhx (pyruvate dehydrogenase complex, component X)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdhx (pyruvate dehydrogenase complex component X)
Pan paniscus (bonobo/pygmy chimpanzee) : PDHX (pyruvate dehydrogenase complex component X)
Canis lupus familiaris (dog) : PDHX (pyruvate dehydrogenase complex component X)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdhx (pyruvate dehydrogenase complex component X)
Sus scrofa (pig) : PDHX (pyruvate dehydrogenase complex component X)
more info ...
Related Pseudogenes: Gm18908  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2103,021,075 - 103,073,513 (-)Ensembl
GRCm382103,021,055 - 103,073,513 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372102,861,212 - 102,913,670 (-)NCBIGRCm37mm9NCBIm37
MGSCv362102,821,916 - 102,874,350 (-)NCBImm8
Celera2104,263,925 - 104,317,607 (-)NCBICelera
Cytogenetic Map2 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pdhx
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1623264
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.