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Gene: Eppk1 (epiplakin 1) Mus musculus
Symbol: Eppk1
Name: epiplakin 1
Description: Exhibits keratin filament binding activity. Involved in several processes, including negative regulation of keratinocyte migration; regulation of epithelial cell proliferation; and regulation of wound healing. Localizes to several cellular components, including apicolateral plasma membrane; basal part of cell; and cell-cell junction. Colocalizes with keratin filament. Is expressed in several structures, including alimentary system; heart ventricle; respiratory system; sensory organ; and skin. Orthologous to human EPPK1 (epiplakin 1); INTERACTS WITH 1,2-dichloroethane; 4,4'-sulfonyldiphenol; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6230424I18Rik; EPIPL; EPIPL1; epiplakin; EPPK
Homo sapiens (human) : EPPK1 (epiplakin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Eppk1 (epiplakin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eppk1 (epiplakin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EPPK1 (epiplakin 1)
Canis lupus familiaris (dog) : EPPK1 (epiplakin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101961294 (epiplakin)
Sus scrofa (pig) : EPPK1 (epiplakin 1)
Chlorocebus sabaeus (African green monkey) : EPPK1 (epiplakin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Annotation category: partial on reference assembly
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1576,101,481 - 76,120,195 (-)EnsemblGRCm38mm10GRCm38
GRCm381576,101,488 - 76,120,195 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371575,932,758 - 75,950,625 (-)NCBIGRCm37mm9NCBIm37
MGSCv361575,929,617 - 75,947,450 (-)NCBImm8
MGSCv361576,602,417 - 76,609,922 (-)NCBImm8
Celera1577,603,256 - 77,619,574 (-)NCBICelera
Cytogenetic Map15D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Eppk1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1623804
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.