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Gene: Eppk1 (epiplakin 1) Mus musculus
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Symbol: Eppk1
Name: epiplakin 1
Description: Exhibits keratin filament binding activity. Involved in several processes, including negative regulation of keratinocyte migration; regulation of epithelial cell proliferation; and regulation of wound healing. Localizes to several cellular components, including apicolateral plasma membrane; basal part of cell; and cell-cell junction. Colocalizes with keratin filament. Is expressed in several structures, including alimentary system; heart ventricle; respiratory system; sensory organ; and skin. Orthologous to human EPPK1 (epiplakin 1); INTERACTS WITH 1,2-dichloroethane; 4,4'-sulfonyldiphenol; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6230424I18Rik; EPIPL; EPIPL1; epiplakin; EPPK
Orthologs:
Homo sapiens (human) : EPPK1 (epiplakin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Eppk1 (epiplakin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eppk1 (epiplakin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EPPK1 (epiplakin 1)
Canis lupus familiaris (dog) : EPPK1 (epiplakin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101961294 (epiplakin)
Sus scrofa (pig) : EPPK1 (epiplakin 1)
Chlorocebus sabaeus (African green monkey) : EPPK1 (epiplakin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1576,101,481 - 76,120,195 (-)EnsemblGRCm38mm10GRCm38
GRCm381576,101,488 - 76,120,195 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371575,932,758 - 75,950,625 (-)NCBIGRCm37mm9NCBIm37
MGSCv361575,929,617 - 75,947,450 (-)NCBImm8
MGSCv361576,602,417 - 76,609,922 (-)NCBImm8
Celera1577,603,256 - 77,619,574 (-)NCBICelera
Cytogenetic Map15D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Eppk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1623804
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.