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Gene: Strc (stereocilin) Mus musculus
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Symbol: Strc
Name: stereocilin
Description: Involved in auditory receptor cell stereocilium organization and detection of mechanical stimulus involved in sensory perception of sound. Localizes to the kinocilium and stereocilium tip. Used to study autosomal recessive nonsyndromic deafness 16. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 16 and sensorineural hearing loss. Is expressed in cochlea; inner ear; semicircular duct ampulla; tectorial membrane; and utricle epithelium. Orthologous to several human genes including STRC (stereocilin); INTERACTS WITH paracetamol; phenobarbital; 6-propyl-2-thiouracil (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DFNB16
Orthologs:
Homo sapiens (human) : STRC (stereocilin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Strc (stereocilin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Strc (stereocilin)
Pan paniscus (bonobo/pygmy chimpanzee) : STRC (stereocilin)
Canis lupus familiaris (dog) : STRC (stereocilin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Strc (stereocilin)
Sus scrofa (pig) : STRC (stereocilin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382121,363,248 - 121,381,370 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372121,189,463 - 121,206,676 (-)NCBIGRCm37mm9NCBIm37
MGSCv362121,055,168 - 121,072,381 (-)NCBImm8
Celera2122,514,641 - 122,531,929 (-)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Strc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1623848
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.