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Gene: Mbd5 (methyl-CpG binding domain protein 5) Mus musculus
Symbol: Mbd5
Name: methyl-CpG binding domain protein 5
Description: Predicted to have chromatin binding activity. Involved in glucose homeostasis; positive regulation of growth hormone receptor signaling pathway; and regulation of growth. Predicted to localize to the chromocenter; midbody; and nucleoplasm. Used to study autosomal dominant non-syndromic intellectual disability. Human ortholog(s) of this gene implicated in autism spectrum disorder and autosomal dominant non-syndromic intellectual disability 1. Is expressed in several structures, including brain; liver; small intestine; spinal cord; and spleen. Orthologous to human MBD5 (methyl-CpG binding domain protein 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; dibenzo[a,l]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9430004D19Rik; AA536666; AI426407; C030040A15Rik; Gm1630; methyl-CpG-binding domain protein 5; methyl-CpG-binding protein MBD5; predicted gene, OTTMUSG00000012483
Homo sapiens (human) : MBD5 (methyl-CpG binding domain protein 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mbd5 (methyl-CpG binding domain protein 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mbd5 (methyl-CpG binding domain protein 5)
Pan paniscus (bonobo/pygmy chimpanzee) : MBD5 (methyl-CpG binding domain protein 5)
Canis lupus familiaris (dog) : MBD5 (methyl-CpG binding domain protein 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mbd5 (methyl-CpG binding domain protein 5)
Sus scrofa (pig) : MBD5 (methyl-CpG binding domain protein 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl248,949,508 - 49,325,405 (+)Ensembl
GRCm38248,949,499 - 49,319,688 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37248,805,028 - 49,172,589 (+)NCBIGRCm37mm9NCBIm37
MGSCv36249,064,365 - 49,139,005 (+)NCBImm8
Celera250,621,661 - 50,990,507 (+)NCBICelera
Cytogenetic Map2 C1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mbd5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1623858
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.