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Gene: Isx (intestine specific homeobox) Mus musculus
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Symbol: Isx
Name: intestine specific homeobox
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of intestinal absorption; regulation of transcription by RNA polymerase II; and regulation of vitamin A metabolic process. Predicted to localize to the nucleus. Is expressed in genitourinary system; midgut; and thymus. Orthologous to human ISX (intestine specific homeobox); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amiodarone (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9130012O13Rik; intestine-specific homeobox; pancreas-intestine homeodomain transcription factor; Pix-1
Orthologs:
Homo sapiens (human) : ISX (intestine specific homeobox)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Isx (intestine-specific homeobox)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Isx (intestine specific homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : ISX (intestine specific homeobox)
Canis lupus familiaris (dog) : ISX (intestine specific homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Isx (intestine specific homeobox)
Sus scrofa (pig) : ISX (intestine specific homeobox)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl874,873,173 - 74,893,506 (+)Ensembl
GRCm38874,873,174 - 74,893,506 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37877,397,073 - 77,417,405 (+)NCBIGRCm37mm9NCBIm37
MGSCv36877,768,789 - 77,789,578 (+)NCBImm8
Celera879,169,160 - 79,189,471 (+)NCBICelera
Cytogenetic Map8 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Isx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1623943
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.