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Gene: Cyp2a4 (cytochrome P450, family 2, subfamily a, polypeptide 4) Mus musculus
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Symbol: Cyp2a4
Name: cytochrome P450, family 2, subfamily a, polypeptide 4
Description: Predicted to have enzyme binding activity; heme binding activity; and monooxygenase activity. Involved in response to stilbenoid. Predicted to localize to cytoplasmic microtubule and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in nicotine dependence. Is expressed in liver; lung; metanephros; nervous system; and nose. Orthologous to several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13) and CYP2A6 (cytochrome P450 family 2 subfamily A member 6); PARTICIPATES IN caffeine pharmacokinetics pathway; cyclophosphamide pharmacodynamics pathway; cyclophosphamide pharmacokinetics pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI893559; Cyp15a1; CYPIIA4; cytochrome P450 2A4; cytochrome P450, 2a4; cytochrome P450-15-alpha; cytochrome P450-IIA3.1; D7Ucla4; testosterone 15-alpha-hydroxylase; testosterone 15alpha-hydroxylase
Orthologs:
Related Pseudogenes: Cyp2a21-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl726,307,169 - 26,315,088 (+)EnsemblGRCm38mm10GRCm38
GRCm38726,307,192 - 26,315,088 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37727,092,211 - 27,100,107 (+)NCBIGRCm37mm9NCBIm37
MGSCv36726,015,952 - 26,023,848 (+)NCBImm8
Celera720,896,679 - 20,902,855 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map714.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cyp2a4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1624100
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.