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Gene: DEFB4B (defensin beta 4B) Homo sapiens
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Symbol: DEFB4B
Name: defensin beta 4B
Description: Exhibits CCR6 chemokine receptor binding activity. Involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; defense response to bacterium; and killing of cells of other organism. Localizes to extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta defensin 2; beta defensin-2; beta-defensin 2; beta-defensin 4B; DEFB4P; defensin, beta 4, pseudogene; defensin, beta 4B
Orthologs:
Mus musculus (house mouse) : Defb7 (defensin beta 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Defb5 (defensin beta 5)  Alliance
Chlorocebus sabaeus (African green monkey) : DEFB4B (defensin beta 4B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl87,894,629 - 7,896,711 (+)EnsemblGRCh38hg38GRCh38
GRCh38 Ensembl87,894,677 - 7,896,716 (+)EnsemblGRCh38hg38GRCh38
GRCh38 Ensembl87,414,855 - 7,416,863 (-)EnsemblGRCh38hg38GRCh38
GRCh3887,414,863 - 7,416,832 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3787,272,385 - 7,274,354 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3687,259,788 - 7,261,795 (-)NCBINCBI36hg18NCBI36
Cytogenetic Map8p23.1NCBI
CHM1_187,353,453 - 7,355,430 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DEFB4B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1625102
Created: 2007-05-20
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.