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Gene: ERN1 (endoplasmic reticulum to nucleus signaling 1) Chlorocebus sabaeus
Symbol: ERN1
Name: endoplasmic reticulum to nucleus signaling 1
Description: ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); endoribonuclease activity (ortholog); INVOLVED IN activation of JUN kinase activity (ortholog); cell cycle arrest (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN Alzheimer's disease pathway; endoplasmic reticulum stress - the unfolded protein response pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); epilepsy (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN AIP1-IRE1 complex (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: serine/threonine-protein kinase/endoribonuclease IRE1
Homo sapiens (human) : ERN1 (endoplasmic reticulum to nucleus signaling 1)  HGNC  Alliance
Mus musculus (house mouse) : Ern1 (endoplasmic reticulum (ER) to nucleus signalling 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ern1 (endoplasmic reticulum to nucleus signaling 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ern1 (endoplasmic reticulum to nucleus signaling 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ERN1 (endoplasmic reticulum to nucleus signaling 1)
Canis lupus familiaris (dog) : ERN1 (endoplasmic reticulum to nucleus signaling 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ern1 (endoplasmic reticulum to nucleus signaling 1)
Sus scrofa (pig) : ERN1 (endoplasmic reticulum to nucleus signaling 1)
Heterocephalus glaber (naked mole-rat) : Ern1 (endoplasmic reticulum to nucleus signaling 1)
more info ...
Latest Assembly: Vervet 1.1 - Green Monkey 1.1 Assembly
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
Vervet 1.1 Ensembl1657,145,191 - 57,236,230 (+)Ensembl
Vervet 1.11657,145,080 - 57,233,757 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on ERN1
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 18433154
Created: 2020-01-22
Species: Chlorocebus sabaeus
Last Modified: 2020-01-22
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.