HAS3 (hyaluronan synthase 3) - Chinchilla Research Resource Database
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Gene: HAS3 (hyaluronan synthase 3) Chlorocebus sabaeus
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Symbol: HAS3
Name: hyaluronan synthase 3
CRRD ID: 18759613
Description: ENCODES a protein that exhibits hyaluronan synthase activity (ortholog); identical protein binding (ortholog); INVOLVED IN extracellular matrix assembly (ortholog); extracellular polysaccharide biosynthetic process (ortholog); hyaluronan biosynthetic process (ortholog); ASSOCIATED WITH fatty liver disease (ortholog); pulmonary hypertension (ortholog); FOUND IN cytoplasm (ortholog); hyaluranon cable (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Orthologs:
Homo sapiens (human) : HAS3 (hyaluronan synthase 3)  HGNC  Alliance
Mus musculus (house mouse) : Has3 (hyaluronan synthase 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Has3 (hyaluronan synthase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Has3 (hyaluronan synthase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : HAS3 (hyaluronan synthase 3)
Canis lupus familiaris (dog) : HAS3 (hyaluronan synthase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Has3 (hyaluronan synthase 3)
Sus scrofa (pig) : HAS3 (hyaluronan synthase 3)
Heterocephalus glaber (naked mole-rat) : Has3 (hyaluronan synthase 3)
more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl558,292,044 - 58,298,524 (-)Ensembl
ChlSab1.1558,289,672 - 58,306,843 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View


Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
HAS3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl558,292,044 - 58,298,524 (-)Ensembl
ChlSab1.1558,289,672 - 58,306,843 (-)NCBI
HAS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1669,105,653 - 69,118,719 (+)EnsemblGRCh38hg38GRCh38
GRCh381669,105,653 - 69,118,719 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371669,139,467 - 69,152,622 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361667,697,661 - 67,710,123 (+)NCBINCBI36hg18NCBI36
Build 341667,697,660 - 67,710,118NCBI
Celera1653,649,484 - 53,661,945 (+)NCBI
Cytogenetic Map16q22.1NCBI
HuRef1655,012,157 - 55,025,357 (+)NCBIHuRef
CHM1_11670,547,541 - 70,560,696 (+)NCBICHM1_1
Has3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398107,596,874 - 107,609,534 (+)NCBI
GRCm388106,870,242 - 106,882,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8106,870,242 - 106,884,566 (+)EnsemblGRCm38mm10GRCm38
MGSCv378109,394,142 - 109,406,802 (+)NCBIGRCm37mm9NCBIm37
MGSCv368109,759,371 - 109,772,031 (+)NCBImm8
Celera8111,096,197 - 111,108,800 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.28NCBI
Has3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01939,063,298 - 39,077,745 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1939,063,998 - 39,077,722 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01949,928,282 - 49,942,033 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41936,718,156 - 36,727,586 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11936,723,036 - 36,732,467 (+)NCBI
Celera1934,192,486 - 34,201,862 (+)NCBICelera
Cytogenetic Map19q12NCBI
Has3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554847,542,286 - 7,570,684 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554847,542,286 - 7,570,108 (-)NCBIChiLan1.0ChiLan1.0
HAS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11668,864,318 - 68,876,678 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1668,868,416 - 68,877,476 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01649,476,561 - 49,488,820 (+)NCBI
HAS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl580,520,261 - 80,529,434 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1580,520,261 - 80,530,769 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Has3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647519,270,788 - 19,282,922 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HAS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl617,843,882 - 17,853,011 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1617,844,974 - 17,870,331 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Has3
(Heterocephalus glaber - naked mole-rat)
No map positions available.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 18 60
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000002130   ⟹   ENSCSAP00000000457
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl558,292,044 - 58,298,524 (-)Ensembl
RefSeq Acc Id: XM_007993820   ⟹   XP_007992011
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.1558,289,672 - 58,302,112 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007993821   ⟹   XP_007992012
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.1558,289,672 - 58,304,380 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007993822   ⟹   XP_007992013
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.1558,289,672 - 58,301,338 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007993823   ⟹   XP_007992014
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.1558,289,672 - 58,301,568 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007993824   ⟹   XP_007992015
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.1558,289,672 - 58,304,380 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007993825   ⟹   XP_007992016
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.1558,289,672 - 58,306,843 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_007992016   ⟸   XM_007993825
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QVR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007992015   ⟸   XM_007993824
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QVR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007992012   ⟸   XM_007993821
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QVR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007992011   ⟸   XM_007993820
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007992014   ⟸   XM_007993823
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QVR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007992013   ⟸   XM_007993822
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QVR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000000457   ⟸   ENSCSAT00000002130


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004101 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCSAP00000000457 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002130 ENTREZGENE, UniProtKB/TrEMBL
InterPro Nucleotide-diphossugar_trans UniProtKB/TrEMBL
NCBI Gene HAS3 ENTREZGENE
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
UniProt A0A0D9QVR8 ENTREZGENE, UniProtKB/TrEMBL

 



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.