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Gene: Furin (furin, paired basic amino acid cleaving enzyme) Heterocephalus glaber
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Symbol: Furin
Name: furin, paired basic amino acid cleaving enzyme
CRRD ID: 18925826
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); nerve growth factor binding (ortholog); peptidase activity (ortholog); INVOLVED IN aging (ortholog); blastocyst formation (ortholog); dibasic protein processing (ortholog); PARTICIPATES IN glypican signaling pathway; hypoxia inducible factor pathway; Notch signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); arteriosclerosis (ortholog); Bloom syndrome (ortholog); FOUND IN cell surface (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: furin preproprotein
Orthologs:
Homo sapiens (human) : FURIN (furin, paired basic amino acid cleaving enzyme)  HGNC  Alliance
Mus musculus (house mouse) : Furin (furin (paired basic amino acid cleaving enzyme))  MGI  Alliance
Rattus norvegicus (Norway rat) : Furin (furin (paired basic amino acid cleaving enzyme))  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Furin (furin, paired basic amino acid cleaving enzyme)
Pan paniscus (bonobo/pygmy chimpanzee) : FURIN (furin, paired basic amino acid cleaving enzyme)
Canis lupus familiaris (dog) : FURIN (furin, paired basic amino acid cleaving enzyme)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Furin (furin, paired basic amino acid cleaving enzyme)
Sus scrofa (pig) : FURIN (furin, paired basic amino acid cleaving enzyme)
Chlorocebus sabaeus (African green monkey) : FURIN (furin, paired basic amino acid cleaving enzyme)
more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position: No map positions available.


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

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More on Furin
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 18925826
Created: 2020-01-23
Species: Heterocephalus glaber
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.