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Gene: Acadm (acyl-CoA dehydrogenase medium chain) Rattus norvegicus
Symbol: Acadm
Name: acyl-CoA dehydrogenase medium chain
CRRD ID: 2012
Description: Exhibits several functions, including acyl-CoA dehydrogenase activity; identical protein binding activity; and nucleotide binding activity. Involved in several processes, including fatty acid catabolic process; response to copper ion; and response to glucocorticoid. Localizes to mitochondrial matrix and mitochondrial membrane. Biomarker of non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in medium chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADM (acyl-CoA dehydrogenase medium chain); PARTICIPATES IN fatty acid beta degradation pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; INTERACTS WITH (+)-schisandrin B; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acetyl-Coenzyme A dehydrogenase, medium chain; acyl-CoA dehydrogenase, C-4 to C-12 straight chain; Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight-chain; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain; acyl-Coenzyme A dehydrogenase, medium chain; MCAD; MCAD, medium chain acyl-CoA dehydrogenase; medium-chain acyl-CoA dehydrogenase; medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Homo sapiens (human) : ACADM (acyl-CoA dehydrogenase medium chain)  HGNC  Alliance
Mus musculus (house mouse) : Acadm (acyl-Coenzyme A dehydrogenase, medium chain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acadm (acyl-CoA dehydrogenase medium chain)
Pan paniscus (bonobo/pygmy chimpanzee) : ACADM (acyl-CoA dehydrogenase medium chain)
Canis lupus familiaris (dog) : ACADM (acyl-CoA dehydrogenase medium chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acadm (acyl-CoA dehydrogenase medium chain)
Sus scrofa (pig) : ACADM (acyl-CoA dehydrogenase medium chain)
Chlorocebus sabaeus (African green monkey) : ACADM (acyl-CoA dehydrogenase medium chain)
Heterocephalus glaber (naked mole-rat) : Acadm (acyl-CoA dehydrogenase medium chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02260,124,418 - 260,148,589 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2260,124,418 - 260,148,589 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02278,788,485 - 278,812,656 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42251,866,645 - 251,890,729 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12251,881,251 - 251,905,336 (-)NCBI
Celera2234,791,302 - 234,815,446 (-)NCBICelera
Cytogenetic Map2q45NCBI
RH 3.4 Map21631.1RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acadm
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2012
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.