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Gene: Acadvl (acyl-CoA dehydrogenase, very long chain) Rattus norvegicus
Symbol: Acadvl
Name: acyl-CoA dehydrogenase, very long chain
CRRD ID: 2014
Description: Exhibits fatty-acyl-CoA binding activity; flavin adenine dinucleotide binding activity; and very-long-chain-acyl-CoA dehydrogenase activity. Involved in fatty acid beta-oxidation. Localizes to mitochondrial inner membrane. Biomarker of non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in very long chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADVL (acyl-CoA dehydrogenase very long chain); PARTICIPATES IN fatty acid beta degradation pathway; carnitine palmitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
Also known as: Acyl-Coa dehydrogenase Very long chain; acyl-Coenzyme A dehydrogenase, very long chain; MGC93660; Very long chain Acyl-Coa dehydrogenase; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; VLCAD; VLCAD very-long-chain acyl-CoA dehydrogenase; VLCAD, very-long-chain acyl-CoA dehydrogenase
Homo sapiens (human) : ACADVL (acyl-CoA dehydrogenase very long chain)  HGNC  Alliance
Mus musculus (house mouse) : Acadvl (acyl-Coenzyme A dehydrogenase, very long chain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acadvl (acyl-CoA dehydrogenase very long chain)
Pan paniscus (bonobo/pygmy chimpanzee) : ACADVL (acyl-CoA dehydrogenase very long chain)
Canis lupus familiaris (dog) : ACADVL (acyl-CoA dehydrogenase very long chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acadvl (acyl-CoA dehydrogenase very long chain)
Sus scrofa (pig) : ACADVL (acyl-CoA dehydrogenase very long chain)
Chlorocebus sabaeus (African green monkey) : ACADVL (acyl-CoA dehydrogenase very long chain)
Heterocephalus glaber (naked mole-rat) : Acadvl (acyl-CoA dehydrogenase very long chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01056,619,321 - 56,624,468 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,619,303 - 56,624,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,364,440 - 56,369,587 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,856,233 - 56,861,380 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11056,869,857 - 56,875,003 (-)NCBI
Celera1053,886,459 - 53,891,606 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acadvl
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2014
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.