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Gene: Asic2 (acid sensing ion channel subunit 2) Rattus norvegicus
Symbol: Asic2
Name: acid sensing ion channel subunit 2
Description: Exhibits voltage-gated sodium channel activity. Involved in several processes, including cellular response to acidic pH; positive regulation of cation channel activity; and sodium ion transport. Predicted to localize to the dendritic spine; integral component of plasma membrane; and neuronal cell body. Orthologous to human ASIC2 (acid sensing ion channel subunit 2); INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; (RS)-amphetamine.
Type: protein-coding
Also known as: Accn1; acid sensing ion channel 2; acid-sensing (proton-gated) ion channel 2; acid-sensing ion channel 2; acid-sensing proton-gated ion channel 2 short variant MDEG2; amiloride-sensitive brain sodium channel 2; amiloride-sensitive cation channel 1; Amiloride-sensitive cation channel 1 neuronal (degenerin); Amiloride-sensitive cation channel 1 neuronal (degenerin) two different splice products: MDEG1 and MDEG2; amiloride-sensitive cation channel 1, neuronal; Amiloride-sensitive cation channel 1, neuronal (degenerin); amiloride-sensitive cation channel neuronal 1; ASIC2a/ASIC2b; BNaC1; BNC1; BNC1k; brain sodium channel 1; degenerin; mammalian degenerin homolog; MDEG; MDEG1; MDEG2
Homo sapiens (human) : ASIC2 (acid sensing ion channel subunit 2)  HGNC  Alliance
Mus musculus (house mouse) : Asic2 (acid-sensing (proton-gated) ion channel 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Asic2 (acid sensing ion channel subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ASIC2 (acid sensing ion channel subunit 2)
Canis lupus familiaris (dog) : ASIC2 (acid sensing ion channel subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asic2 (acid sensing ion channel subunit 2)
Sus scrofa (pig) : ASIC2 (acid sensing ion channel subunit 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01068,247,800 - 69,347,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01067,915,396 - 68,982,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41069,103,244 - 70,190,305 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11069,117,480 - 69,386,966 (-)NCBI
Celera1064,828,913 - 65,888,336 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Asic2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2017
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.