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Gene: Actg2 (actin gamma 2, smooth muscle) Rattus norvegicus
Symbol: Actg2
Name: actin gamma 2, smooth muscle
CRRD ID: 2027
Description: Predicted to have ATP binding activity. Predicted to be involved in mesenchyme migration; positive regulation of gene expression; and vascular associated smooth muscle contraction. Predicted to localize to several cellular components, including dynactin complex; lamellipodium; and myosin filament. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human ACTG2 (actin gamma 2, smooth muscle); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
Also known as: ACTGE; Actin gamma 2 smooth muscle enteric; actin, gamma 2; actin, gamma 2, smooth muscle, enteric; actin, gamma-enteric smooth muscle; alpha-actin-3; alpha-smooth muscle actin; gamma-2-actin; gamma-enteric smooth muscle actin; MGC105507; SMGA; smooth muscle gamma-actin
Homo sapiens (human) : ACTG2 (actin gamma 2, smooth muscle)  HGNC  Alliance
Mus musculus (house mouse) : Actg2 (actin, gamma 2, smooth muscle, enteric)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Actg2 (actin gamma 2, smooth muscle)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTG2 (actin gamma 2, smooth muscle)
Canis lupus familiaris (dog) : ACTG2 (actin gamma 2, smooth muscle)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actg2 (actin gamma 2, smooth muscle)
Sus scrofa (pig) : ACTG2 (actin gamma 2, smooth muscle)
Chlorocebus sabaeus (African green monkey) : ACTG2 (actin gamma 2, smooth muscle)
Heterocephalus glaber (naked mole-rat) : Actg2 (actin gamma 2, smooth muscle)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04115,215,160 - 115,239,746 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4115,215,060 - 115,239,723 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04179,805,782 - 179,830,362 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,732,482 - 117,747,006NCBIRGSC3.4rn4RGSC3.4
Celera4105,015,569 - 105,030,100 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Actg2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2027
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.