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Gene: Acvrl1 (activin A receptor like type 1) Rattus norvegicus
Symbol: Acvrl1
Name: activin A receptor like type 1
Description: Predicted to have several functions, including ATP binding activity; activin binding activity; and transmembrane receptor protein serine/threonine kinase activity. Involved in response to hypoxia. Localizes to cell surface; dendrite; and neuronal cell body. Biomarker of pulmonary hypertension and transient cerebral ischemia. Human ortholog(s) of this gene implicated in hereditary hemorrhagic telangiectasia and pulmonary hypertension. Orthologous to human ACVRL1 (activin A receptor like type 1); PARTICIPATES IN activin signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
Also known as: activin A receptor type II-like 1; activin A receptor type IL; Activin receptor like kinase 1; activin receptor like kinase 1; Alk1; MGC91691; R-3; R3; serine/threonine-protein kinase receptor R3; SETHKIR; SKR3; TGF-B superfamily receptor type I; TSR-I
Homo sapiens (human) : ACVRL1 (activin A receptor like type 1)  HGNC  Alliance
Mus musculus (house mouse) : Acvrl1 (activin A receptor, type II-like 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvrl1 (activin A receptor like type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVRL1 (activin A receptor like type 1)
Canis lupus familiaris (dog) : ACVRL1 (activin A receptor like type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvrl1 (activin A receptor like type 1)
Sus scrofa (pig) : ACVRL1 (activin A receptor like type 1)
Chlorocebus sabaeus (African green monkey) : ACVRL1 (activin A receptor like type 1)
Heterocephalus glaber (naked mole-rat) : Acvrl1 (activin A receptor like type 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07142,769,942 - 142,787,336 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,776,252 - 142,787,335 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07140,571,236 - 140,588,083 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47139,873,596 - 139,884,675 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17139,944,251 - 139,961,111 (+)NCBI
Celera7128,712,554 - 128,723,633 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acvrl1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2029
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.