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Gene: Adcy6 (adenylate cyclase 6) Rattus norvegicus
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Symbol: Adcy6
Name: adenylate cyclase 6
Description: Exhibits several functions, including SNARE binding activity; calcium- and calmodulin-responsive adenylate cyclase activity; and protein kinase binding activity. Involved in several processes, including cAMP biosynthetic process; maintenance of protein location in plasma membrane; and negative regulation of neuron projection development. Localizes to the endosome; membrane raft; and microvillus membrane. Colocalizes with the sarcolemma. Biomarker of ureteral obstruction. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human ADCY6 (adenylate cyclase 6); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; glucagon signaling pathway; protein kinase A (PKA) signaling pathway; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AC6; ACVI; ADCYB; adenylate cyclase type 6; adenylate cyclase type VI; adenylyl cyclase 6; ATP pyrophosphate-lyase 6; ca(2+)-inhibitable adenylyl cyclase
Orthologs:
Homo sapiens (human) : ADCY6 (adenylate cyclase 6)  HGNC  Alliance
Mus musculus (house mouse) : Adcy6 (adenylate cyclase 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adcy6 (adenylate cyclase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ADCY6 (adenylate cyclase 6)
Canis lupus familiaris (dog) : ADCY6 (adenylate cyclase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcy6 (adenylate cyclase 6)
Sus scrofa (pig) : ADCY6 (adenylate cyclase 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07140,270,678 - 140,291,722 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X114,774,376 - 114,795,062 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,339,933 - 137,360,020 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17137,418,113 - 137,437,246 (-)NCBI
Celera7126,233,455 - 126,254,162 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Adcy6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2035
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.