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Gene: Add3 (adducin 3) Rattus norvegicus
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Symbol: Add3
Name: adducin 3
Description: Exhibits protein kinase C binding activity. Involved in positive regulation of vasoconstriction and response to drug. Localizes to the cytoskeleton. Used to study hypertension. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 50. Orthologous to human ADD3 (adducin 3); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adducin 3 (gamma); adducin 3, gamma; adducin-like protein 70; gamma-adducin; potein kinase C binding protein 35H; protein kinase C-binding protein 35H
Orthologs:
Homo sapiens (human) : ADD3 (adducin 3)  HGNC  Alliance
Mus musculus (house mouse) : Add3 (adducin 3 (gamma))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Add3 (adducin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ADD3 (adducin 3)
Canis lupus familiaris (dog) : ADD3 (adducin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Add3 (adducin 3)
Sus scrofa (pig) : ADD3 (adducin 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01273,854,195 - 273,961,982 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1273,854,248 - 273,961,982 (+)Ensembl
Rnor_5.01281,267,424 - 281,375,203 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41259,347,673 - 259,455,407 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11259,560,471 - 259,923,891 (-)NCBI
Celera1247,872,140 - 247,979,623 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Add3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2043
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.