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Gene: Parp1 (poly (ADP-ribose) polymerase 1) Rattus norvegicus
Symbol: Parp1
Name: poly (ADP-ribose) polymerase 1
Description: Exhibits several functions, including NAD+ ADP-ribosyltransferase activity; R-SMAD binding activity; and estrogen receptor binding activity. Involved in several processes, including cellular response to amyloid-beta; regulation of nucleobase-containing compound metabolic process; and regulation of signal transduction. Localizes to cytoplasm and nucleus. Used to study congestive heart failure; middle cerebral artery infarction; and transient cerebral ischemia. Biomarker of several diseases, including borna disease; cerebrovascular disease (multiple); kidney failure; perinatal necrotizing enterocolitis; and ureteral obstruction. Human ortholog(s) of this gene implicated in several diseases, including arthritis; asthma; bacterial meningitis; neurodegenerative disease (multiple); and stomach carcinoma. Orthologous to human PARP1 (poly(ADP-ribose) polymerase 1); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; base excision repair pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (+)-sesamin.
Type: protein-coding
Also known as: ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase); ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; Adprt; ADPRT 1; ARTD1; DNA ADP-ribosyltransferase PARP1; MGC93658; NAD(+) ADP-ribosyltransferase 1; Parp-1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); poly [ADP-ribose] polymerase 1; Poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) polymerase, PARP-1; poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1
Homo sapiens (human) : PARP1 (poly(ADP-ribose) polymerase 1)  HGNC  Alliance
Mus musculus (house mouse) : Parp1 (poly (ADP-ribose) polymerase family, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Parp1 (poly(ADP-ribose) polymerase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PARP1 (poly(ADP-ribose) polymerase 1)
Canis lupus familiaris (dog) : PARP1 (poly(ADP-ribose) polymerase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Parp1 (poly(ADP-ribose) polymerase 1)
Sus scrofa (pig) : PARP1 (poly(ADP-ribose) polymerase 1)
Chlorocebus sabaeus (African green monkey) : PARP1 (poly(ADP-ribose) polymerase 1)
Heterocephalus glaber (naked mole-rat) : Parp1 (poly(ADP-ribose) polymerase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01398,857,255 - 98,889,444 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1398,857,177 - 98,889,716 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013103,859,760 - 103,891,949 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,309,670 - 96,341,486 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11396,498,605 - 96,530,421 (+)NCBI
Celera1391,853,812 - 91,885,580 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)