Gene: Adra2a (adrenoceptor alpha 2A) Rattus norvegicus
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Symbol: Adra2a
Name: adrenoceptor alpha 2A
Description: Exhibits alpha2-adrenergic receptor activity; involved in several processes, including DNA replication, G protein-coupled receptor signaling pathway, and negative regulation of transport; localizes to several cellular components, including the GABA-ergic synapse, axon terminus, and intrinsic component of plasma membrane; used to study anxiety disorder and mental depression; biomarker of hypertension and type 2 diabetes mellitus; orthologous to human ADRA2A (adrenoceptor alpha 2A); INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; 2,3,4,7,8-Pentachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Adrenergic alpha 2A receptor; adrenergic receptor, alpha 2a; Adrenergic, alpha 2A, receptor; adrenergic, alpha-2A-, receptor; alpha-2A adrenergic receptor; alpha-2A adrenoceptor; alpha-2A adrenoreceptor; alpha-2AAR; alpha-2D adrenergic receptor; CA2-47; RATRG20; RG20
Orthologs:
Homo sapiens (human) : ADRA2A (adrenoceptor alpha 2A)  HGNC  Alliance
Mus musculus (house mouse) : Adra2a (adrenergic receptor, alpha 2a)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adra2a (adrenoceptor alpha 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA2A (adrenoceptor alpha 2A)
Canis lupus familiaris (dog) : ADRA2A (adrenoceptor alpha 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adra2a (adrenoceptor alpha 2A)
Sus scrofa (pig) : ADRA2A (adrenoceptor alpha 2A)
more info ...
Allele / Splice: Adra2aem1Mcwi  
Genetic Models: SS-Adra2aem1Mcwi-/- SS-Adra2aem1Mcwi
Is Marker For: Strains:   F344.GK-(D1Swe8-D1Gpam-1)/Swe  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01274,766,283 - 274,769,083 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01282,178,475 - 282,181,275 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1248,775,483 - 248,778,283 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Adra2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2056
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.