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Gene: Adra2c (adrenoceptor alpha 2C) Rattus norvegicus
Symbol: Adra2c
Name: adrenoceptor alpha 2C
Description: Predicted to have several functions, including alpha-2A adrenergic receptor binding activity; alpha2-adrenergic receptor activity; and protein dimerization activity. Involved in several processes, including negative regulation of uterine smooth muscle contraction; positive regulation of vasoconstriction; and regulation of sensory perception of pain. Localizes to several cellular components, including the glutamatergic synapse; integral component of postsynaptic density membrane; and neuronal cell body. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human ADRA2C (adrenoceptor alpha 2C); INTERACTS WITH (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin; 3H-1,2-dithiole-3-thione; ammonium chloride.
Type: protein-coding
Also known as: Adrenergic alpha2C- receptor class I; adrenergic receptor, alpha 2c; adrenergic, alpha-2C-, receptor; Adrenergic, alpha2C-, receptor class I; alpha-2 adrenergic receptor subtype C4; alpha-2C adrenergic receptor; alpha-2C adrenoceptor; alpha-2C adrenoreceptor; alpha-2CAR
Homo sapiens (human) : ADRA2C (adrenoceptor alpha 2C)  HGNC  Alliance
Mus musculus (house mouse) : Adra2c (adrenergic receptor, alpha 2c)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA2C (adrenoceptor alpha 2C)
Canis lupus familiaris (dog) : ADRA2C (adrenoceptor alpha 2C)
Sus scrofa (pig) : ADRA2C (adrenoceptor alpha 2C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01480,730,307 - 80,732,010 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01481,422,130 - 81,423,833 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,107,907 - 81,109,610 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11481,110,297 - 81,112,001 (-)NCBI
Celera1474,399,360 - 74,401,063 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Adra2c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2058
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.