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Gene: Adrb1 (adrenoceptor beta 1) Rattus norvegicus
Symbol: Adrb1
Name: adrenoceptor beta 1
CRRD ID: 2059
Description: Exhibits beta1-adrenergic receptor activity. Involved in several processes, including positive regulation of transport; regulation of blood circulation; and regulation of muscle system process. Localizes to cytoplasm; nucleus; and plasma membrane. Used to study congestive heart failure; dilated cardiomyopathy; myocardial infarction; periodontitis; and renovascular hypertension. Biomarker of hyperglycemia; hypertension; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; hypertension (multiple); low tension glaucoma; obstructive sleep apnea; and periodontitis. Orthologous to human ADRB1 (adrenoceptor beta 1); PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; 3',5'-cyclic AMP.
Type: protein-coding
Also known as: Adrenergic receptor beta 1; adrenergic receptor, beta 1; adrenergic, beta-1-, receptor; B1AR; beta 1-adrenergic receptor beta 1-AR; beta 1-adrenergic receptor, beta 1-AR; beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor; RATB1AR
Homo sapiens (human) : ADRB1 (adrenoceptor beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Adrb1 (adrenergic receptor, beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adrb1 (adrenoceptor beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRB1 (adrenoceptor beta 1)
Canis lupus familiaris (dog) : ADRB1 (adrenoceptor beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adrb1 (adrenoceptor beta 1)
Sus scrofa (pig) : ADRB1 (adrenoceptor beta 1)
Chlorocebus sabaeus (African green monkey) : ADRB1 (adrenoceptor beta 1)
Heterocephalus glaber (naked mole-rat) : Adrb1 (adrenoceptor beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01277,537,585 - 277,538,985 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1277,537,585 - 277,538,985 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01284,917,872 - 284,919,272 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41263,025,655 - 263,027,055 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11263,236,699 - 263,238,100 (+)NCBI
Celera1251,470,349 - 251,471,554 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Adrb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2059
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.