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Gene: Agrp (agouti related neuropeptide) Rattus norvegicus
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Symbol: Agrp
Name: agouti related neuropeptide
Description: Predicted to have neuropeptide hormone activity and type 1 melanocortin receptor binding activity. Involved in several processes, including adult feeding behavior; long-day photoperiodism; and positive regulation of feeding behavior. Localizes to extracellular space and neuronal cell body. Biomarker of obesity and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human AGRP (agouti related neuropeptide); PARTICIPATES IN altered melanocortin system pathway; melanocortin system pathway; obesity pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-deoxy-D-glucose; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Agouti (mouse) related protein; agouti related protein; agouti related protein homolog (mouse); Agouti-related protein
Orthologs:
Homo sapiens (human) : AGRP (agouti related neuropeptide)  HGNC  Alliance
Mus musculus (house mouse) : Agrp (agouti related neuropeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Agrp (agouti related neuropeptide)
Pan paniscus (bonobo/pygmy chimpanzee) : AGRP (agouti related neuropeptide)
Canis lupus familiaris (dog) : AGRP (agouti related neuropeptide)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agrp (agouti related neuropeptide)
Sus scrofa (pig) : AGRP (agouti related neuropeptide)
Chlorocebus sabaeus (African green monkey) : AGRP (agouti related neuropeptide)
Heterocephalus glaber (naked mole-rat) : Agrp (agouti related neuropeptide)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01937,525,941 - 37,584,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,526,419 - 37,528,011 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,391,845 - 48,406,659 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,386,682 - 35,388,274 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11935,391,672 - 35,392,244 (-)NCBI
Celera1932,876,306 - 32,877,927 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Agrp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2068
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.