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Gene: Ak4 (adenylate kinase 4) Rattus norvegicus
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Symbol: Ak4
Name: adenylate kinase 4
Description: Predicted to have adenylate kinase activity; nucleoside diphosphate kinase activity; and nucleoside triphosphate adenylate kinase activity. Involved in brain development; liver development; and response to drug. Predicted to localize to the mitochondrial matrix. Biomarker of acute kidney tubular necrosis. Orthologous to human AK4 (adenylate kinase 4); PARTICIPATES IN de novo purine biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,2,2-tetramine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adenylate kinase 3 alpha-like 1; adenylate kinase 3-like 1; adenylate kinase 3-like 2; adenylate kinase 4, mitochondrial; adenylate kinase isoenzyme 4; adenylate kinase isoenzyme 4, mitochondrial; AK 4; Ak3l1; Ak3l2; ATP-AMP transphosphorylase; GTP:AMP phosphotransferase AK4; GTP:AMP phosphotransferase AK4, mitochondrial; MGC93541
Orthologs:
Homo sapiens (human) : AK4 (adenylate kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Ak4 (adenylate kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ak4 (adenylate kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : AK4 (adenylate kinase 4)
Canis lupus familiaris (dog) : AK4 (adenylate kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ak4 (adenylate kinase 4)
Sus scrofa (pig) : AK4 (adenylate kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05120,250,318 - 120,309,153 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05124,129,933 - 124,189,606 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45122,062,872 - 122,119,335 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15122,068,045 - 122,127,564 (+)NCBI
Celera5114,576,993 - 114,626,919 (+)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ak4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2078
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.