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Gene: Aldh1a1 (aldehyde dehydrogenase 1 family, member A1) Rattus norvegicus
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Symbol: Aldh1a1
Name: aldehyde dehydrogenase 1 family, member A1
CRRD ID: 2087
Description: Exhibits benzaldehyde dehydrogenase (NAD+) activity; identical protein binding activity; and retinal dehydrogenase activity. Involved in several processes, including estrous cycle; response to estradiol; and retinoic acid metabolic process. Localizes to cytoplasm and nucleus. Orthologous to human ALDH1A1 (aldehyde dehydrogenase 1 family member A1); PARTICIPATES IN retinoic acid metabolic pathway; cyclophosphamide pharmacodynamics pathway; cyclophosphamide pharmacokinetics pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ahd2; Aldehyde dehydrogenase 1; Aldehyde dehydrogenase 1 subfamily A1; Aldehyde dehydrogenase 1, subfamily A1; aldehyde dehydrogenase 1A1; aldehyde dehydrogenase 2; aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase family 1, member A1; aldehyde dehydrogenase family 1, subfamily A1; aldehyde dehydrogenase, cytosolic; ALDH-E1; Aldh1; Aldh2; ALHDII; RALDH 1; ralDH1; retinal dehydrogenase 1
Orthologs:
Homo sapiens (human) : ALDH1A1 (aldehyde dehydrogenase 1 family member A1)  HGNC  Alliance
Mus musculus (house mouse) : Aldh1a1 (aldehyde dehydrogenase family 1, subfamily A1)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ALDH1A1 (aldehyde dehydrogenase 1 family member A1)
Canis lupus familiaris (dog) : ALDH1A1 (aldehyde dehydrogenase 1 family member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aldh1a1 (aldehyde dehydrogenase 1 family member A1)
Sus scrofa (pig) : ALDH1A1 (aldehyde dehydrogenase 1 family member A1)
Chlorocebus sabaeus (African green monkey) : ALDH1A1 (aldehyde dehydrogenase 1 family member A1)
Heterocephalus glaber (naked mole-rat) : Aldh1a1 (aldehyde dehydrogenase 1 family member A1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01238,222,689 - 238,264,381 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,222,521 - 238,264,330 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01245,340,587 - 245,562,970 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,731,675 - 223,773,285 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11223,895,697 - 223,937,307 (+)NCBI
Celera1215,379,207 - 215,421,068 (+)NCBICelera
Cytogenetic Map1q51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Aldh1a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2087
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.