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Gene: Amd1 (adenosylmethionine decarboxylase 1) Rattus norvegicus
Symbol: Amd1
Name: adenosylmethionine decarboxylase 1
Description: Exhibits adenosylmethionine decarboxylase activity and putrescine binding activity. Involved in S-adenosylmethionine metabolic process; spermidine biosynthetic process; and spermine biosynthetic process. Localizes to cytosol. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human AMD1 (adenosylmethionine decarboxylase 1); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; putrescine metabolic pathway; INTERACTS WITH 3H-1,2-dithiole-3-thione; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adoMetDC; Amd1a; Amd1b; S-adenosylmethionine decarboxylase 1; S-Adenosylmethionine decarboxylase 1A; S-Adenosylmethionine decarboxylase 1B; S-adenosylmethionine decarboxylase proenzyme; SAMDC
Homo sapiens (human) : AMD1 (adenosylmethionine decarboxylase 1)  HGNC  Alliance
Mus musculus (house mouse) : Amd1 (S-adenosylmethionine decarboxylase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amd1 (adenosylmethionine decarboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AMD1 (adenosylmethionine decarboxylase 1)
Canis lupus familiaris (dog) : AMD1 (adenosylmethionine decarboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amd1 (adenosylmethionine decarboxylase 1)
Sus scrofa (pig) : AMD1 (adenosylmethionine decarboxylase 1)
Chlorocebus sabaeus (African green monkey) : AMD1 (adenosylmethionine decarboxylase 1)
Heterocephalus glaber (naked mole-rat) : Amd1 (adenosylmethionine decarboxylase 1)
more info ...
Related Pseudogenes: Amd1-ps1   Amd1-ps2   Amd1-ps3  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02045,384,000 - 45,399,694 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2045,384,000 - 45,399,694 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02047,103,749 - 47,119,386 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42044,452,475 - 44,468,111 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12044,475,485 - 44,491,122 (-)NCBI
Celera2044,399,688 - 44,415,381 (-)NCBICelera
Cytogenetic Map20q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Amd1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2104
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.