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Gene: Amelx (amelogenin, X-linked) Rattus norvegicus
Symbol: Amelx
Name: amelogenin, X-linked
CRRD ID: 2107
Description: Exhibits identical protein binding activity. Involved in response to calcium ion; response to drug; and response to nutrient. Localizes to Golgi apparatus; endocytic vesicle; and extracellular matrix. Biomarker of autosomal dominant hypocalcemia. Human ortholog(s) of this gene implicated in amelogenesis imperfecta and amelogenesis imperfecta type 1E. Orthologous to several human genes including AMELX (amelogenin X-linked); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Amel; amelogenin; amelogenin X chromosome; amelogenin, X isoform; leucine-rich amelogenin peptide; LRAP
Homo sapiens (human) : AMELX (amelogenin X-linked)  HGNC  Alliance
Mus musculus (house mouse) : Amelx (amelogenin, X-linked)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amelx (amelogenin X-linked)
Pan paniscus (bonobo/pygmy chimpanzee) : AMELX (amelogenin X-linked)
Canis lupus familiaris (dog) : AMELX (amelogenin X-linked)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amelx (amelogenin X-linked)
Sus scrofa (pig) : AMELX (amelogenin X-linked)
Heterocephalus glaber (naked mole-rat) : Amelx (amelogenin X-linked)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X26,439,197 - 26,450,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX26,439,197 - 26,450,495 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X26,843,989 - 26,855,287 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X45,763,451 - 45,769,374 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X45,816,919 - 45,822,842 (+)NCBI
CeleraX25,496,279 - 25,507,557 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Amelx
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2107
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.