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Gene: Apbb1 (amyloid beta precursor protein binding family B member 1) Rattus norvegicus
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Symbol: Apbb1
Name: amyloid beta precursor protein binding family B member 1
Description: Exhibits amyloid-beta binding activity and tau protein binding activity. Involved in several processes, including histone H4 acetylation; positive regulation of neuron projection development; and positive regulation of nucleobase-containing compound metabolic process. Localizes to several cellular components, including the neuron projection; perinuclear region of cytoplasm; and synaptic membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human APBB1 (amyloid beta precursor protein binding family B member 1); PARTICIPATES IN Alzheimer's disease pathway; INTERACTS WITH (RS)-amphetamine; 3H-1,2-dithiole-3-thione; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: amyloid beta (A4) precursor protein-binding, family B, member 1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65); amyloid beta A4 precursor protein-binding family B member 1; amyloid-beta A4 precursor protein-binding family B member 1; FE65
Orthologs:
Is Marker For: Strains:   SHRSP.WKY-(Apbb1-D1Arb21)/Izm  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01170,387,625 - 170,411,263 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01177,393,531 - 177,417,140 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,282,918 - 163,299,333 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11163,378,394 - 163,394,810 (-)NCBI
Celera1157,829,568 - 157,845,995 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Apbb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2122
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.