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Gene: Aplp2 (amyloid beta precursor like protein 2) Rattus norvegicus
Symbol: Aplp2
Name: amyloid beta precursor like protein 2
Description: Predicted to have identical protein binding activity. Predicted to be involved in several processes, including brain development; regulation of epidermal growth factor-activated receptor activity; and suckling behavior. Predicted to localize to nucleus. Used to study Alzheimer's disease. Biomarker of neurodegenerative disease. Orthologous to human APLP2 (amyloid beta precursor like protein 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: amyloid beta (A4) precursor-like protein 2; amyloid beta (A4) precursor-like protein 2-like; Amyloid protein precursor-like protein 2; amyloid-like protein 2; APLP-2; Apph; LOC100363366; LOC64312; sperm membrane protein (YWK-II); sperm membrane protein YWK-II; WALPLP2
Homo sapiens (human) : APLP2 (amyloid beta precursor like protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Aplp2 (amyloid beta (A4) precursor-like protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aplp2 (amyloid beta precursor like protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : APLP2 (amyloid beta precursor like protein 2)
Canis lupus familiaris (dog) : APLP2 (amyloid beta precursor like protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aplp2 (amyloid beta precursor like protein 2)
Sus scrofa (pig) : APLP2 (amyloid beta precursor like protein 2)
Chlorocebus sabaeus (African green monkey) : APLP2 (amyloid beta precursor like protein 2)
Heterocephalus glaber (naked mole-rat) : Aplp2 (amyloid beta precursor like protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0832,298,526 - 32,328,821 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl832,298,532 - 32,328,839 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0832,323,516 - 32,353,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera831,060,571 - 31,122,969 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Aplp2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2128
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.