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Gene: Apob (apolipoprotein B) Rattus norvegicus
Symbol: Apob
Name: apolipoprotein B
Description: Predicted to have several functions, including anion binding activity; cholesterol transfer activity; and lipase binding activity. Involved in several processes, including cellular response to tumor necrosis factor; response to estradiol; and triglyceride catabolic process. Localizes to several cellular components, including high-density lipoprotein particle; low-density lipoprotein particle; and very-low-density lipoprotein particle. Biomarker of fatty liver disease and nephrotic syndrome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Orthologous to human APOB (apolipoprotein B); PARTICIPATES IN altered lipoprotein metabolic pathway; forkhead class A signaling pathway; lipoprotein metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Aa1064; Ac1-060; Apo B-100; ApoB-100; ApoB-48; apolipoprotein B (including Ag(x) antigen); apolipoprotein B PI; apolipoprotein B-100; apolipoprotein B-48
Homo sapiens (human) : APOB (apolipoprotein B)  HGNC  Alliance
Mus musculus (house mouse) : Apob (apolipoprotein B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apob (apolipoprotein B)
Pan paniscus (bonobo/pygmy chimpanzee) : APOB (apolipoprotein B)
Canis lupus familiaris (dog) : APOB (apolipoprotein B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apob (apolipoprotein B)
Sus scrofa (pig) : APOB (apolipoprotein B)
Chlorocebus sabaeus (African green monkey) : APOB (apolipoprotein B)
Heterocephalus glaber (naked mole-rat) : Apob (apolipoprotein B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0633,176,826 - 33,216,381 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl633,176,778 - 33,224,997 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0642,956,372 - 42,995,922 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4631,508,060 - 31,548,083 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1631,546,139 - 31,550,758 (+)NCBI
Celera630,299,724 - 30,339,330 (+)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Apob
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2129
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.