Gene: Apoc2 (apolipoprotein C2) Rattus norvegicus
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Symbol: Apoc2
Name: apolipoprotein C2
Description: Predicted to have several functions, including enzyme regulator activity; phospholipase binding activity; and protein homodimerization activity. Involved in lipoprotein transport and response to drug. Predicted to localize to several cellular components, including the low-density lipoprotein particle; spherical high-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Human ortholog(s) of this gene implicated in familial hyperlipidemia; familial lipoprotein lipase deficiency; and multiple sclerosis. Orthologous to human APOC2 (apolipoprotein C2); PARTICIPATES IN altered lipoprotein metabolic pathway; lipoprotein metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; caffeine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apolipoprotein C-II; LOC292697; RGD1560725; similar to Apolipoprotein C2
Orthologs:
Homo sapiens (human) : APOC2 (apolipoprotein C2)  HGNC  Alliance
Mus musculus (house mouse) : Apoc2 (apolipoprotein C-II)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoc2 (apolipoprotein C2)
Pan paniscus (bonobo/pygmy chimpanzee) : APOC2 (apolipoprotein C2)
Canis lupus familiaris (dog) : APOC2 (apolipoprotein C2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoc2 (apolipoprotein C2)
Sus scrofa (pig) : APOC2 (apolipoprotein C2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0180,589,023 - 80,593,991 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0181,854,610 - 81,859,580 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,979,034 - 78,984,002 (-)NCBIRGSC3.4rn4RGSC3.4
Celera173,788,729 - 73,793,701 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Apoc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2135
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.