Gene: Aqp1 (aquaporin 1 (Colton blood group)) Rattus norvegicus
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Symbol: Aqp1
Name: aquaporin 1 (Colton blood group)
Description: Exhibits glycerol transmembrane transporter activity and water channel activity; involved in several processes, including glycerol transport, hyperosmotic salinity response, and lateral ventricle development; localizes to several cellular components, including the apical plasma membrane, axon terminus, and basolateral plasma membrane; predicted to colocalize with the symbiont-containing vacuole membrane; biomarker of artery disease (multiple), autosomal recessive polycystic kidney disease, brain disease (multiple), diabetes mellitus, and eye disease (multiple); orthologous to human AQP1 (aquaporin 1 (Colton blood group)); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol; 2,2,2-tetramine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AQP-1; aquaporin 1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); aquaporin-1; aquaporin-CHIP; CHIP28; water channel protein for red blood cells and kidney proximal tubule
Orthologs:
Homo sapiens (human) : AQP1 (aquaporin 1 (Colton blood group))  HGNC  Alliance
Mus musculus (house mouse) : Aqp1 (aquaporin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aqp1 (aquaporin 1 (Colton blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : AQP1 (aquaporin 1 (Colton blood group))
Canis lupus familiaris (dog) : AQP1 (aquaporin 1 (Colton blood group))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aqp1 (aquaporin 1 (Colton blood group))
Sus scrofa (pig) : AQP1 (aquaporin 1 (Colton blood group))
more info ...
Is Marker For: Strains:   SD  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0485,551,503 - 85,563,683 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04150,203,461 - 150,215,641 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4484,098,346 - 84,110,524 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1484,384,810 - 84,396,991 (+)NCBI
Celera479,349,727 - 79,361,905 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Aqp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2141
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.