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Gene: Asns (asparagine synthetase (glutamine-hydrolyzing)) Rattus norvegicus
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Symbol: Asns
Name: asparagine synthetase (glutamine-hydrolyzing)
Description: Exhibits asparagine synthase (glutamine-hydrolyzing) activity; cofactor binding activity; and protein homodimerization activity. Involved in several processes, including asparagine biosynthetic process; cellular response to glucose starvation; and response to methotrexate. Predicted to localize to the cytosol. Biomarker of hepatocellular carcinoma. Orthologous to human ASNS (asparagine synthetase (glutamine-hydrolyzing)); PARTICIPATES IN Canavan disease pathway; alanine, aspartate and glutamate metabolic pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: asparagine synthetase; asparagine synthetase [glutamine-hydrolyzing]; glutamine-dependent asparagine synthetase; MGC93148
Orthologs:
Homo sapiens (human) : ASNS (asparagine synthetase (glutamine-hydrolyzing))  HGNC  Alliance
Mus musculus (house mouse) : Asns (asparagine synthetase)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ASNS (asparagine synthetase (glutamine-hydrolyzing))
Canis lupus familiaris (dog) : ASNS (asparagine synthetase (glutamine-hydrolyzing))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asns (asparagine synthetase (glutamine-hydrolyzing))
Sus scrofa (pig) : ASNS (asparagine synthetase (glutamine-hydrolyzing))
more info ...
Is Marker For: Strains:   BB/OK  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0433,742,876 - 33,761,106 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0433,608,301 - 33,626,631 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4432,758,866 - 32,776,220 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1432,877,146 - 32,895,094 (-)NCBI
Celera431,290,059 - 31,307,413 (-)NCBICelera
Cytogenetic Map4q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Asns
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2162
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.