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Gene: Atp1b1 (ATPase Na+/K+ transporting subunit beta 1) Rattus norvegicus
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Symbol: Atp1b1
Name: ATPase Na+/K+ transporting subunit beta 1
Description: Exhibits sodium:potassium-exchanging ATPase activity. Predicted to contribute to ATP binding activity; ATPase activity; and alkali metal ion binding activity. Involved in potassium ion transport; response to hypoxia; and sodium ion transport. Localizes to several cellular components, including the basolateral plasma membrane; caveola; and sodium:potassium-exchanging ATPase complex. Biomarker of sensorineural hearing loss. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to human ATP1B1 (ATPase Na+/K+ transporting subunit beta 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATPase Na+/K+ transporting beta 1 polypeptide; ATPase, Na+/K+ transporting, beta 1 polypeptide; ATPBS; Na,K-ATPase beta 1 subunit; sodium/potassium-dependent ATPase subunit beta-1; sodium/potassium-transporting ATPase subunit beta-1
Orthologs:
Homo sapiens (human) : ATP1B1 (ATPase Na+/K+ transporting subunit beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Atp1b1 (ATPase, Na+/K+ transporting, beta 1 polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp1b1 (ATPase Na+/K+ transporting subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP1B1 (ATPase Na+/K+ transporting subunit beta 1)
Canis lupus familiaris (dog) : ATP1B1 (ATPase Na+/K+ transporting subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp1b1 (ATPase Na+/K+ transporting subunit beta 1)
Sus scrofa (pig) : ATP1B1 (ATPase Na+/K+ transporting subunit beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01382,737,161 - 82,757,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01387,621,447 - 87,641,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41380,214,056 - 80,234,576 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11380,228,241 - 80,249,087 (-)NCBI
Celera1376,517,954 - 76,538,475 (-)NCBICelera
Cytogenetic Map13q23NCBI
RH 3.4 Map13485.8RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Atp1b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2170
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.