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Gene: Fxyd2 (FXYD domain-containing ion transport regulator 2) Rattus norvegicus
Symbol: Fxyd2
Name: FXYD domain-containing ion transport regulator 2
CRRD ID: 2173
Description: Predicted to have sodium channel regulator activity. Involved in several processes, including cellular hyperosmotic salinity response; negative regulation of cell population proliferation; and negative regulation of sodium:potassium-exchanging ATPase activity. Localizes to basolateral plasma membrane; intracellular membrane-bounded organelle; and sodium:potassium-exchanging ATPase complex. Human ortholog(s) of this gene implicated in renal hypomagnesemia 2. Orthologous to human FXYD2 (FXYD domain containing ion transport regulator 2); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP1C; Atp1g1; ATPase Na+/K+ transporting gamma 1 polypeptide; ATPase, Na+/K+ transporting, gamma 1 polypeptide; FXTD domain-containing ion transport regulator 2; gamma subunit of sodium potassium ATPase; GNAKATP; na(+)/K(+) ATPase subunit gamma; sodium pump gamma chain; sodium/potassium-transporting ATPase gamma chain; sodium/potassium-transporting ATPase subunit gamma
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0849,710,334 - 49,717,492 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,710,477 - 49,716,955 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0848,336,046 - 48,343,177 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4848,379,075 - 48,385,553 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1848,387,840 - 48,394,319 (+)NCBI
Celera845,295,931 - 45,302,409 (+)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Fxyd2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2173
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.